What is divigel estradiol gel?

Divigel (estradiol gel) is a clear, colorless gel, which is odorless when dry. Estradiol is a form of estrogen, a female sex hormone that regulates many processes in the body. Divigel is used to treat certain symptoms of menopause such as hot flashes, and vaginal dryness, burning, and irritation.

In this regard, is divigel the same as Estrogel?

OBJECTIVE: Divigel and Estrogel are estradiol gels for the treatment of postmenopausal women with moderate to severe vasomotor symptoms. They differ with respect to several factors including estradiol concentration and surface application, and cannot be compared solely on the basis of their estradiol dose.

Secondly, what are the side effects of divigel? Common side effects of Divigel include:

  • nausea.
  • vomiting.
  • loss of appetite.
  • swollen breasts.
  • acne or skin color changes.
  • vaginal pain/dryness/discomfort.
  • decreased sex drive.
  • difficulty having an orgasm.

Considering this, what is estradiol gel used for?

Estradiol topical gel is also used to treat vaginal dryness, itching, and burning in women who are experiencing menopause. However, women whose only bothersome symptoms are vaginal burning, itching, and dryness may benefit more from a medication that is applied topically to the vagina.

How long does divigel take to dry?

It's important to take Divigel® once a day as directed. This will help your body sustain a more consistent level of estrogen to relieve your symptoms. Let the gel dry completely before dressing. Wait at least 1 hour before bathing or swimming.

Where do you apply divigel?

Divigel should be applied once daily on the skin of either the right or left upper thigh. The application surface area should be about 5 by 7 inches (approximately the size of two palm prints). Use the gel at the same time each day. The entire contents of a unit dose packet should be applied each day.

What is divigel made from?

The remaining components of the gel (carbomer, ethanol, propylene glycol, purified water, and triethanolamine) are pharmacologically inactive. Divigel® provides estrogen therapy by delivering estradiol, the major estrogenic hormone secreted by the human ovary, to the systemic circulation following topical application.

What are the benefits of estradiol?

Estradiol is used to treat menopause symptoms such as hot flashes and vaginal changes, and to prevent osteoporosis (bone loss) in menopausal women. Estradiol is also used to treat low estrogen levels in women with ovarian failure. It is also indicated to treat certain types of breast cancer and prostate cancer.

How quickly does estradiol work?

It can take up to 4 months to see the full effect of the estrogens. Your doctor may reconsider continuing your estrogen treatment or may lower your dose several times within the first one or two months, and every 3 to 6 months after that.

Can estradiol cause hair loss?

Estrogen is related to hair growth — and hair loss. While estrogen levels are high, women have full, thick hair. But when they drop, such as after a pregnancy or during and after menopause, more hair enters the "resting" phase, where it soon falls out and causes thinning and even balding patches.

Where is the best place to apply EstroGel?

Spread the Estrogel as thinly as possible over the entire area on the inside and outside of your arm from wrist to shoulder. Never apply Estrogel directly to the breast. Always place the small protective cap back on the tip of the pump and the large pump cover over the top of the pump after each use.

Is estradiol made from horse urine?

The estrogen-replacement drug Premarin, prescribed to menopausal women, is made from horse urine; in fact, the drug's name is short for PREgnant MARes' urINe. About 750,000 mares are impregnated each year for the sole purpose of collecting their estrogen-rich urine.

Which is better estrogen patch or gel?

CONCLUSIONS: We concluded that, in our environment, the use of 17-beta estradiol in gel presented fewer local skin reactions, was more effective in alleviating the symptoms of hypoestrogenism and had better acceptance in hormone replacement therapy for menopausal women, as compared with the 17-beta estradiol patch.

Does estradiol cause weight gain?

One form of estrogen called estradiol decreases at menopause. This hormone helps to regulate metabolism and body weight. Lower levels of estradiol may lead to weight gain. Throughout their life, women may notice weight gain around their hips and thighs.

Can I take estradiol every other day?

Estradiol tablets in doses of 0.5 milligrams (mg), 1 mg, or 2 mg are typically given on a daily basis. They can also be prescribed to be taken for three weeks, followed by one week of no medication. The tablets can be taken more than once a day for some conditions.

Where do you rub estrogen cream?

Estrogen Optimal Use
  • Spread estrogen preferably on the following locations with thin skin: the outer and inner sides of both your arms and shoulders, inner sides of both your thighs, your abdomen (if slender), or your face (may reduce facial hair and wrinkles).
  • Always use the same skin surfaces so the absorption is stable and constant.

Does divigel cause hair loss?

The most common side effects for all estrogen products are headache, breast pain, irregular vaginal bleeding or spotting, stomach/abdominal cramps and bloating, nausea and vomiting, and hair loss.

What is the benefit of taking estrogen?

Other benefits of taking Estrogen as HT include: Reduced risk of developing osteoporosis and reduced risk of bone breakage. Improvement of mood and overall sense of mental well-being in some women. Decreased tooth loss.

Can divigel cause depression?

Tell your doctor right away if you have any serious side effects, including: mental/mood changes (such as depression, memory loss), breast lumps, unusual vaginal bleeding (such as spotting, breakthrough bleeding, prolonged/recurrent bleeding), increased or new vaginal irritation/itching/odor/discharge, severe stomach/

Can divigel cause high blood pressure?

Blood pressure: Increased blood pressure is not uncommon for women using this medication. Blood pressure should be monitored with estrogen use, especially if high doses are used.

Do you gain weight with hormone replacement therapy?

Although it is believed that estrogen therapy (HRT) is a cause of weight gain for women, the researchers say that is not the case, and HRT can help women lose the unwanted belly fat that appears post-menopause. This means, for all women, being thoughtful about what you eat and for many, being more active every day.

Where do you apply EstroGel?

Using your hand, apply EstroGel to the skin of your other arm.
  1. Spread the gel as thinly as possible from your wrist to your shoulder.
  2. Do not massage or rub in EstroGel. Allow the gel to dry for up to 5 minutes before you get dressed.
  3. Do not apply EstroGel directly to your breasts or in and around your vagina.

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